ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
Impact of PASTEUR: 9.9m lives saved, ROI of 125:1
What does an antibiotic cost to develop? What is it worth? How to afford it?
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
Melinta goes bankrupt / Never let a good crisis go to waste
The 6 meanings of “Lack of Access” (UNSLAP)
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Lancet: 10-20-30 targets to address AMR by 2030
In Praise of Non-Inferiority
Scary, Scarier, Scariest (Part 2): What can YOU do about it?
Categories of resistance: MDR, XDR, PDR, UDR, and (new!) DTR
News from Davos 2020: Some positive signs, but overall a fragile antibiotic market at a tipping point
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet